Clozapine
From SNPedia
Clozapine is an antipsychotic medication used in the treatment of schizophrenia. It is generally used only when other drugs have failed, due to the risk of developing side effects (including agranulocytosis). Clozapine is sold (usually by Novartis) under brand names such as Clozaril, Leponex, Fazaclo, and Froidir. Wikipedia
Several SNPs have been studied with regard to clozapine, including:
A non-FDA regulated genetic test is also marketed by a company claiming to have evidence linking a particular SNP to risk for agranulocytosis upon treatment with clozapine; however, the SNP apparently is not named using dbSNP terminology, and there is a paucity of peer-reviewed, published information about this association.
