rs924607(T;T)
From SNPedia
| in childhood acute lymphoblastic leukemia patients, worse response to vincristine |
| Is a | genotype |
| of | rs924607 |
| Gene | LOC100996325, LOC105374608 |
| Chromosome | 5 |
| Position | 609,978 |
| mentioned | by |
| Magnitude | 1.5 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;T) | 0 | common/normal |
| (T;T) | 1.5 | in childhood acute lymphoblastic leukemia patients, worse response to vincristine |
(T;T) pediatric ALL patients being treated with vincristine have twice the risk of developing peripheral neuropathies compared to (C;C) and (C;T) patients, based on a preliminary study of ~300 patients.
