| Associated with Alcohol Dependence; associated with nicotine dependence (female) |
| Geno
|
Mag
|
Summary
|
| (C;C)
|
2.5
|
Associated with Alcohol Dependence; associated with nicotine dependence (female)
|
| (T;T)
|
0
|
common/normal
|
[PMID 22085192] Cannabinoid Receptor 1 Gene is Associated with Alcohol Dependence.
Alcoholic patients with TGT haplotype (corresponding to rs6454674-rs1049353-rs806368 polymorphisms in this order) were less prone to have AD (p = 0.017). TGC haplotype were more likely to develop AD.
[PMID 18606954] Cannabinoid receptor 1 gene association with nicotine dependence.
the associations were female specific. Haplotype 1-1-2 of markers rs2023239-rs12720071-rs806368(C) was associated with nicotine dependence and FTND score in the 2 samples (P < .001 and P = .009, respectively).
