Part of a haplotype Gs286, standalone effect for endometrial cancer is ambiguous. Tightly linked with PROGINS allele rs1042838.
No statistically significant interaction with 17-alpha-hydroxyprogesterone caproate for reducing recurrent preterm birth detected. [PMID 21600550
]
| GWAS snp
|
| PMID
|
[PMID 20547493]
|
| Trait
|
Endometrial cancer
|
| Title
|
Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach.
|
| Risk Allele
|
T
|
| P-val
|
0.47
|
| Odds Ratio
|
1.18 [0.96-1.45]
|
[PMID 22105149] Progestogen levels, progesterone receptor gene polymorphisms, and mammographic density changes: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study
[PMID 21600550] Progesterone receptor polymorphisms and clinical response to 17-alpha-hydroxyprogesterone caproate
[PMID 15632380] Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis
]
