| 3.57x increased risk of MGUS |
| Geno
|
Mag
|
Summary
|
| (A;A)
|
1
|
Normal risk for development of MGUS
|
| (A;G)
|
1
|
Possibly slight 1.09x risk for development of MGUS
|
| (G;G)
|
2
|
3.57x increased risk of MGUS
|
This genotype confers an increased risk of the development of MGUS (Monoclonal Gammopathy of Uncertain Significance). OR=3.57 95% CI=1.67-7.65. The G allele is the minor allele and the risk allele, and appears to function in a recessive manner in increasing risk, as the AG heterozygote has nearly the same risk as the AA homozygote.
