||<0.63x risk for restless legs
||0.63x risk for restless legs
||Normal risk of developing restless legs syndrome
rs9357271, a SNP located in the BTBD9 gene region, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.63 (CI: 0.52-0.75) for the (C) minor allele. [PMID 17637780]
This SNP may also be associated with Tourette syndrome (TS), particularly TS without obsessive-compulsive disorder, based on a study of ~600 patients.[PMID 19822783]
|Desc||RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 6|
||Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.
[PMID 23361623] The BTBD9 gene may be associated with antipsychotic-induced restless legs syndrome in schizophrenia
[PMID 22914617] Analysis of the BTBD9 and HTR2C variants in Chinese Han patients with Tourette syndrome.
[PMID 26597663] Genetic factors influencing ferritin levels in 14,126 blood donors: results from the Danish Blood Donor Study
[PMID 28329290] Association of BTBD9 and MAP2K5/SKOR1 With Restless Legs Syndrome in Chinese Population.