|(C;T)||2||1.23x risk for colorectal cancer|
|(T;T)||2||1.70x risk for colorectal cancer|
Inheriting the risk variant at both SNP loci (i.e. rs4779584 and rs6983267) is estimated to increase the overall risk of developing colorectal cancer about 3 fold. The authors of this study are quoted as saying that "the lifetime risk [of bowel cancer] is about 5% in the UK so it's going up to 7% or so if you've got both bad copies of a variant." nature
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|Odds Ratio||1.23 [1.14-1.34]|
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|Odds Ratio||1.1800 [1.11-1.24]|
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|Odds Ratio||1.12 [1.08-1.19]|
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