http://www.medhours.com/master-gene-controls-fat-metabolism/ The enrichment of rs4731702 trans associations for low P values suggests that KLF14 is a master regulator of gene expression in adipose tissue
| GWAS snp
|
| PMID
|
[PMID 20686565 ]
|
| Trait
|
|
| Title
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
| Risk Allele
|
T
|
| P-val
|
1E-15
|
| Odds Ratio
|
0.5900 None
|
[PMID 19936222] Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
[PMID 24195066] Association of the KLF14 rs4731702 SNP and Serum Lipid Levels in the Guangxi Mulao and Han Populations
[PMID 22702842] Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease.
[PMID 23630301] Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
| GWAS snp
|
| PMID
|
[PMID 24097068]
|
| Trait
|
HDL cholesterol
|
| Title
|
Discovery and refinement of loci associated with lipid levels.
|
| Risk Allele
|
T
|
| P-val
|
5E-17
|
| Odds Ratio
|
.03 [NR] unit increase
|
]
