|(A;A)||3x increased gastric cancer risk. Increased risk of Acute Graft-Versus-Host Disease after Unrelated Bone Marrow Transplantation|
|(A;G)||1.4x increased gastric cancer risk. Increased risk of Acute Graft-Versus-Host Disease after Unrelated Bone Marrow Transplantation|
A study of 811 Japanese subjects (524 without gastric cancer and 287 with gastric cancer) reported an odds ratio of 1.42 (CI: 1.09-1.85, p=0.01) for the rs2275913(A) allele, and 3.02 (CI: 1.86-4.91, p<0.0001) for the (A;A) genotype, with gastric cancer.[PMID 19414056]
[PMID 19724898] Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa
[PMID 20437253] The Polymorphism of IL-17 G-152A was Associated with Childhood Asthma and Bacterial Colonization of the Hypopharynx in Bronchiolitis
This "A"-allele of this SNP is also functionally associated with acute Graft-Versus-Host Disease after unrelated bone marrow transplantation 10.1371/journal.pone.0026229
[PMID 22028838] A Genetic Variant in the IL-17 Promoter Is Functionally Associated with Acute Graft-Versus-Host Disease after Unrelated Bone Marrow Transplantation
[PMID 22118860] Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese - A case control study
[PMID 22483685] Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Behcet's disease in Korean population
[PMID 22461912] Association Analysis of IL-17A and IL-17F Polymorphisms in Chinese Han Women with Breast Cancer
[PMID 17828618] The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis.
[PMID 19208686] Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand.
[PMID 19235914] Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease.
[PMID 20620187] Interleukin-17 gene polymorphism is associated with Vogt-Koyanagi-Harada syndrome but not with Behcet's disease in a Chinese Han population.
[PMID 21217785] A single nucleotide polymorphism of IL-17 gene in the recipient is associated with acute GVHD after HLA-matched unrelated BMT.
[PMID 22692973] Interleukin-17 gene polymorphisms are associated with bladder cancer in a Chinese Han population.
[PMID 23049595] Association between IL17 Polymorphisms and Risk of Cervical Cancer in Chinese Women
[PMID 23131423] Interleukin-17A genetic variants can confer resistance to brucellosis in Iranian population
[PMID 23376081] Analysis of IL-17 gene polymorphisms in Chinese patients with dilated cardiomyopathy
[PMID 23652560] Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population
[PMID 23137879] Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis
[PMID 23485736] Polymorphisms in immune/inflammatory cytokine genes are related to Parkinson's disease with cognitive impairment in the Han Chinese population
[PMID 24315816] Effect of interleukin-17A and interleukin-17F gene polymorphisms on the risk of gastric cancer in a Chinese population
[PMID 22537748] Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3'-UTR, influence susceptibility to gastric cancer.
[PMID 22559912] Increased activity of interleukin-23/interleukin-17 cytokine axis in primary antiphospholipid syndrome.
[PMID 22816799] Association of interleukin-17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases.
[PMID 22955700] Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis.
[PMID 23219503] The IL-17F sequence variant is associated with susceptibility to tuberculosis.
[PMID 23280722] IL17A gene polymorphisms, serum IL-17A and IgE levels, and hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection.
[PMID 23778030] The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain.
[PMID 24857622] IL-17F but not IL-17A gene polymorphism confers risk to multiple sclerosis in a Chinese Han population
[PMID 24919468] Influence of the IL17A locus in giant cell arteritis susceptibility
[PMID 25012243] IL-17 gene polymorphism is associated with susceptibility to gastric cancer
[PMID 25227691] Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women
[PMID 25374195] Meta-analysis of Associations between Interleukin-17 Gene Polymorphisms and Risk of Gastric Cancer
[PMID 25680555] Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression
[PMID 25857634] Genetic Polymorphisms in the Toll-like Receptor 10, Interleukin (IL)17A and IL17F genes differently affect the risk for Tuberculosis in Croatian population
[PMID 25871515] Association between interleukin 17A polymorphisms and susceptibility to rheumatoid arthritis in a Chinese population
[PMID 25595174] Specific association of IL17A genetic variants with panuveitis
[PMID 26339129] The Influence of Interleukin 17A and IL17F Polymorphisms on Chronic Periodontitis Disease in Brazilian Patients
[PMID 26337284] Association study between IL-17A and IL-17F gene polymorphism and myasthenia gravis in Chinese patients
[PMID 26400516] Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus
[PMID 26436389] Correlation between polymorphisms in the IL-17A and IL-17F genes and development of coronary artery disease
[PMID 26447633] Influence of the IL17A and IL17F genes polymorphisms on the long-term kidney allograft function and return to dialysis after kidney transplantation
[PMID 26467330] Interleukin-17 and leptin genes polymorphisms and their levels in relation to recurrent pregnancy loss in Egyptian females
[PMID 24776844] Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
[PMID 26515887] Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis
[PMID 26535650] Role of IL-17 gene polymorphisms in the susceptibility to gastric cancer
[PMID 26535675] Association analysis of rs2275913G>A and rs763780T>C interleukin 17 polymorphisms in Chinese women with cervical cancer
[PMID 26546176] Association of IL-17A and IL-17F gene polymorphisms with chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: A case-control study
[PMID 29050281] IL-23R and IL-17A polymorphisms correlate with susceptibility of ankylosing spondylitis in a Southwest Chinese population.
[PMID 29194748] Interleukin-17 and Toll -like Receptor 10 genetic polymorphisms and susceptibility to large joint osteoarthrits.
[PMID 29262579] The association of IL-17A polymorphisms with IL-17A serum levels and risk of ischemic stroke.
[PMID 29530464] Role of gene polymorphisms/haplotypes and serum levels of interleukin-17A in susceptibility to viral myocarditis.
[PMID 29689450] Association of interleukin-17A polymorphisms with the risk of colorectal cancer: A case-control study.
[PMID 29933861] Interleukin-17 A and F gene polymorphisms affect the risk of tuberculosis: An updated meta-analysis.
[PMID 30130760] Genes Regulating Immune Response and Amelogenesis Interact in Increasing the Susceptibility to Molar-Incisor Hypomineralization.
[PMID 30275190] IL-8-251T>A (rs4073) Polymorphism Is Associated with Prognosis in Gastric Cancer Patients.
[PMID 30446888] Association Between the Interleukin-17 Gene Polymorphism -197G>A and the Risk of Prostate Cancer in a Galician Population.
[PMID 30655311] Correlations of IL-17 and NF-κB gene polymorphisms with susceptibility and prognosis in Acute Respiratory Distress Syndrome in a Chinese population.
[PMID 31042000] Alternative Interleukin (IL)17A/F Locus Haplotypes are associated with increased risk to hip and knee osteoarthritis.
[PMID 31845023] Genetic polymorphism patterns suggest a genetic driven inflammatory response as pathogenesis in appendicitis.