[PMID 19254294] Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.
|Title||Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways|
|Odds Ratio||1.27 None|
[PMID 19796199] Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease
[PMID 19533685] Common genetic variants and risk for non-Hodgkin lymphoma and adult T-cell lymphoma/leukemia in Jamaica
[PMID 20332709] Association analysis of polymorphisms in IL-3, IL-4, IL-5, IL-9 and IL-13 with Graves' disease
[PMID 20403202] Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study
[PMID 20975284] Case-Control Study of Eczema Associated with IL13 Genetic Polymorphisms in Japanese Children
[PMID 20484924] Interleukin 13 and interleukin 4 receptor-? polymorphisms in rhinitis and asthma
[PMID 21196282] Single nucleotide polymorphisms in IL-4Ra, IL-13 and STAT6 genes occurs in brain glioma
[PMID 21309855] A meta-analysis of Th2 pathway genetic variants and risk for allergic rhinitis
[PMID 22013915] IL13 genetic polymorphisms, smoking, and eczema in women: a case-control study in Japan
[PMID 22023794] Case-control study of IL13 polymorphisms, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study
[PMID 22053598] Association of TGF-beta1, IL-4 and IL-13 gene polymerphisms with asthma in a Chinese population
[PMID 22286212] Genome-Wide Association Study of Classical Hodgkin Lymphoma and Epstein-Barr Virus Status-Defined Subgroups
|Title||A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.|
|Odds Ratio||0.0800 None|
[PMID 22419714] Effect of Type 2 Diabetes Predisposing Genetic Variants on Colorectal Cancer Risk
[PMID 22432974] Environmental tobacco smoke and male sex modify the influence of IL-13 genetic variants on cord blood IgE levels
|Disease||Asthma Allergic rhinitis|
|CLNDBN||Asthma, susceptibility to Allergic rhinitis, susceptibility to|
|CLNSRC||OMIM Allelic Variant|
[PMID 15660293] No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.
[PMID 15726497] Gene-environment interaction effects on the development of immune responses in the 1st year of life.
[PMID 16024651] Polymorphisms associated with asthma are inversely related to glioblastoma multiforme.
[PMID 16449530] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.
[PMID 16702372] Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity.
[PMID 16759385] Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA).
[PMID 16832637] Evaluation of interleukin 13 polymorphisms in systemic sclerosis.
[PMID 17135570] Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping.
[PMID 17303794] Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.
[PMID 17327408] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.
[PMID 17346294] IL13 gene polymorphism association with cord serum immunoglobulin E.
[PMID 17561245] Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.
[PMID 17615386] IL13 promoter polymorphism 1112C/T modulates the adverse effect of tobacco smoking on lung function.
[PMID 17705862] Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.
[PMID 18006935] An international case-control study of interleukin-4Ralpha, interleukin-13, and cyclooxygenase-2 polymorphisms and glioblastoma risk.
[PMID 18056382] Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.
[PMID 18075513] Variants in the 5q31 cytokine gene cluster are associated with psoriasis.
[PMID 18410415] Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.
[PMID 18614543] The 5q31 variants associated with psoriasis and Crohn's disease are distinct.
[PMID 18633131] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.
[PMID 18676870] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.
[PMID 18687755] Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population.
[PMID 18778477] Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
[PMID 18846228] Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.
[PMID 19066394] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.
[PMID 19262574] Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.
[PMID 19356949] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.
[PMID 19554022] Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking.
[PMID 19759553] Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort.
[PMID 19840389] Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 19956102] Evidence for association of the TCF7 locus with type I diabetes.
[PMID 19956106] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.
[PMID 19956109] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.
[PMID 20015396] Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.
[PMID 20298583] Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.
[PMID 20358028] IL-13 Gene Polymorphisms are Associated With Rhinosinusitis and Eosinophilic Inflammation in Aspirin Intolerant Asthma.
[PMID 20406895] Genetic variants in inflammation pathway genes and asthma in glioma susceptibility.
[PMID 20606885] Genetics of psoriasis and psoriatic arthritis.
[PMID 20811626] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
[PMID 20952689] Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma.
[PMID 21253569] Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
[PMID 21320344] Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.
[PMID 21349879] Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris.
[PMID 21613309] IL13 gene polymorphism is a marker for psoriatic arthritis among psoriasis patients.
[PMID 21913997] Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.
[PMID 22045834] Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression.
[PMID 22201026] Genome-wide pathway analysis of a genome-wide association study on psoriasis and Behcet's disease.
[PMID 22222605] IL-13 polymorphisms contribute to the risk of asthma: a meta-analysis.
[PMID 22376040] Gene-gene interactions between candidate gene polymorphisms are associated with total IgE levels in Korean children with asthma.
|qualified_impact||Insufficiently evaluated pharmacogenetic|
[PMID 22534877] Follow-up study of the first genome-wide association scan in alopecia areata: IL13 and KIAA0350 as susceptibility loci supported with genome-wide significance
[PMID 23171465] Association between non-atopic hand eczema and interleukin-13 gene polymorphism in Taiwanese nursing population
[PMID 23545317] Association of interleukin-13 SNP rs20541 with allergic rhinitis risk: a meta-analysis
[PMID 23617596] Genetic variants of the genes encoding zinc finger protein 313 and interleukin-13 confer a risk for psoriasis in a Chinese Uygur population
[PMID 23200760] Pathway analysis of genome-wide association study on asthma
[PMID 23299779] Interleukin-10 gene polymorphisms are associated with freedom from treatment failure for patients with Hodgkin lymphoma
[PMID 23267696] Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study
[PMID 23954258] Association of Interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore
[PMID 23978640] Association of IL-13 gene polymorphisms with airway hyperresponsiveness in a Japanese adult asthmatic population
[PMID 24286397] Association between the interleukin-13 gene and development of chronic obstructive pulmonary disease in southern Chinese Han population: a case-control study
|Title||A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.|
|Odds Ratio||.07 [0.043-0.101] unit increase|
[PMID 22694930] Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
[PMID 23246181] Association between IL13 gene polymorphisms and susceptibility to cancer: a meta-analysis.
[PMID 23395224] Association between polymorphisms in interleukin-4Ralpha and interleukin-13 and glioma risk: a meta-analysis.
[PMID 23462527] IL4R and IL13 polymorphic variants and development of antibodies to surface antigen of hepatitis B virus in hemodialysis patients in response to HBV vaccination or infection.
[PMID 23663310] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.
[PMID 23815671] Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study.
[PMID 25658755] Association between Polymorphism of the Interleukin-13 Gene and Susceptibility to Hepatocellular Carcinoma in the Chinese Population
[PMID 26258681] An IL-13 Promoter Polymorphism Associated with Liver Fibrosis in Patients with Schistosoma japonicum
[PMID 26426602] Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study
[PMID 26516307] Single Nucleotide Polymorphisms in IL-10, IL-12p40, and IL-13 Genes and Susceptibility to Glioma
[PMID 28289589] Polymorphism of the IL13 gene may be associated with Uterine leiomyomas in Slovenian women.
[PMID 29017771] Association of interleukin 13 gene polymorphisms and plasma IL 13 level with risk of systemic lupus erythematosus.