||2x increased risk for Hodgkin lymphoma
||3.5x increased risk for Hodgkin lymphoma
|?|| (A;A) (A;G) (G;G) ||28|
rs1585215 is a SNP in the NFKB1 gene.
A population-based case-control study including 473 cases of Hodgkin lymphoma concluded that increased risk for the disease was significantly associated with rs1585215. The odds ratio for rs1585215(G;G) homozygotes was 3.5 (CI: 2.2-5.7, Ptrend = 1.7 x 10(-8)), and for (A;G) heterozygotes, 2.1 (CI: 1.5-2.9).[PMID 19223558]
[PMID 25422198] Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang