rs1537415
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | normal |
| (C;G) | 1.6 | 1.6x increased risk for periodontitis |
| (G;G) | 2 | 2x increased risk for periodontitis |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 135637876 |
| Gene | GLT6D1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1537415 |
| dbSNP (classic) | rs1537415 |
| ClinGen | rs1537415 |
| ebi | rs1537415 |
| HLI | rs1537415 |
| Exac | rs1537415 |
| Gnomad | rs1537415 |
| Varsome | rs1537415 |
| LitVar | rs1537415 |
| Map | rs1537415 |
| PheGenI | rs1537415 |
| Biobank | rs1537415 |
| 1000 genomes | rs1537415 |
| hgdp | rs1537415 |
| ensembl | rs1537415 |
| geneview | rs1537415 |
| scholar | rs1537415 |
| rs1537415 | |
| pharmgkb | rs1537415 |
| gwascentral | rs1537415 |
| openSNP | rs1537415 |
| 23andMe | rs1537415 |
| SNPshot | rs1537415 |
| SNPdbe | rs1537415 |
| MSV3d | rs1537415 |
| GWAS Ctlg | rs1537415 |
| GMAF | 0.3131 |
| Max Magnitude | 2 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs1537415 is an intronic SNP in the glycosyltransferase 6 domain containing 1 GLT6D1 gene.
In a combined study of 1,758 Dutch and German subjects, the rs1537415(G) allele was associated with increased risk for periodontitis, at an odds ratio of 1.59 (CI: 1.36-1.86, p=5.5x10e-9).[PMID 19897590]
[PMID 25682733] Replication of the association of GLT6D1 with aggressive periodontitis in a Sudanese population
