|| 1.59x increased risk of developing bipolar disorder (one study)
|| 1.32x increased risk of developing bipolar disorder (one study)
|| Normal risk of developing bipolar disorder
|?|| (C;C) (C;T) (T;T) ||28|
, a SNP in the DPP10
gene, has been reported in a large study to be associated with bipolar disorder
The risk allele (oriented to the dbSNP entry) is (C) ; the odds ratio associated with heterozygotes is 1.32 (CI 1.07-1.63), and for homozygotes, 1.59 (CI 1.29-1.96). [Note: the 2009 citation below did not see a statistically significant difference between cases and controls for this allele in their study.][PMID 17554300]
|| [PMID 21254220]
|| Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
| Risk Allele
| Odds Ratio
|| None None
[PMID 19308021] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.