rs1361600

minus

Geno	Mag	Summary
(A;A)	0
(G;G)	2	~2x increased risk for adult-onset asthma in Japanese populations

Make rs1361600(A;G)

Reference

GRCh38 38.1/141

Chromosome

1

Position

94542362

Gene

F3

is a	snp
is	mentioned by
dbSNP	rs1361600
dbSNP (classic)	rs1361600
ClinGen	rs1361600
ebi	rs1361600
HLI	rs1361600
Exac	rs1361600
Gnomad	rs1361600
Varsome	rs1361600
LitVar	rs1361600
Map	rs1361600
PheGenI	rs1361600
Biobank	rs1361600
1000 genomes	rs1361600
hgdp	rs1361600
ensembl	rs1361600
geneview	rs1361600
scholar	rs1361600
google	rs1361600
pharmgkb	rs1361600
gwascentral	rs1361600
openSNP	rs1361600
23andMe	rs1361600
SNPshot	rs1361600
SNPdbe	rs1361600
MSV3d	rs1361600
GWAS Ctlg	rs1361600

GMAF

0.4435

Max Magnitude

2

?

(A;A) (A;G) (G;G)

28

rs1361600, also known as -603A>G, is a SNP in the promoter region of the coagulation factor III (aka thromboplastin or tissue factor) F3 gene.

Two unrelated Japanese populations both showed an association between rs1361600(G;G) and adult-onset asthma, with an odds ratio of ~2 (p=.02 or .06).[PMID 20150920]

[PMID 19583819] Tissue factor gene polymorphisms and haplotypes and the risk of ischemic vascular events: four studies and a meta-analysis.

[PMID 23274712 ] Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.

[PMID 25407675 ] Genetic variation in the tissue factor gene is associated with clinical outcome in severe sepsis patients