Also known as Ile462Val A4889G CYP1A1*2C
[PMID 19351467] [Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene.]
[PMID 19168589] Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China
[PMID 19608585] Genetic association study of CYP1A1 polymorphisms identifies risk haplotypes in non-small cell lung cancer
[PMID 20544687] Evidence that genetic variants of metabolic detoxication and cell cycle control are not related to gallbladder cancer risk in Chilean women
[PMID 15942023] Genome amplification of single sperm using multiple displacement amplification.
[PMID 16026601] Decision forest analysis of 61 single nucleotide polymorphisms in a case-control study of esophageal cancer; a novel method.
[PMID 16412218] Multilocus analysis of SNP and metabolic data within a given pathway.
[PMID 16949388] CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.
[PMID 17116718] Dietary phytoestrogen intake is associated with reduced colorectal cancer risk.
[PMID 17548691] Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
[PMID 17603290] Cytochrome P450 1A1 (CYP1A1) polymorphisms and breast cancer risk in Korean women.
[PMID 18191955] Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.
[PMID 18298806] Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years.
[PMID 18601742] Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.
[PMID 18628428] Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.
[PMID 18632753] Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
[PMID 18691756] Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk.
[PMID 18763031] CYP1A1 and CYP1B1 genetic polymorphisms and uterine leiomyoma risk in Chinese women.
[PMID 18787887] Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 18980759] Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect.
[PMID 18990750] Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.
[PMID 18992263] Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
[PMID 19127255] Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.
[PMID 19174490] Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.
[PMID 19267064] [Relationship between genetic polymorphisms of phase I and phase II metabolizing enzymes and DNA damage of workers exposed to vinyl chloride monomer].
[PMID 19287484] Clique-finding for heterogeneity and multidimensionality in biomarker epidemiology research: the CHAMBER algorithm.
[PMID 19330903] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
[PMID 19338043] Genetic polymorphisms in glutathione S-transferases and cytochrome P450s, tobacco smoking, and risk of non-Hodgkin lymphoma.
[PMID 19479063] Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.
[PMID 19537956] CYP1A1 genotype modifies the impact of smoking on effectiveness of HAART among women.
[PMID 19630952] Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.
[PMID 19899130] Polymorphisms of drug-metabolizing genes and risk of non-Hodgkin lymphoma.
[PMID 19954069] [Association of nasopharyngeal carcinoma risk with cytochrome P450 CYP1A1 gene polymorphisms].
[PMID 20878621] Impact of CYP1A1 and COMT genotypes on breast cancer risk in Mexican women: a pilot study.
[PMID 21254355] Smoking, the xenobiotic pathway, and clubfoot.
[PMID 21429951] Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.
[PMID 21708280] Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis.
[PMID 22426923] Pharmacogenetic assessment of clinical outcome in patients with metastatic breast cancer treated with docetaxel plus capecitabine.
[PMID 22525558] Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population.
|qualified_impact||Insufficiently evaluated pharmacogenetic|
[PMID 23785672] Genetic polymorphisms in CYP1A1, CYP1B1 and COMT genes in Greenlandic Inuit and Europeans
[PMID 24084248] The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes
[PMID 24320736] Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: A case-control study
[PMID 23816456] CYP1A1 genetic polymorphism and polycyclic aromatic hydrocarbons on pulmonary function in the elderly: haplotype-based approach for gene-environment interaction
[PMID 24499375] Association of Oxidative Stress Related Genes with Idiopathic Recurrent Miscarriage
[PMID 22949524] Gene-environment interaction in preterm delivery with special reference to organochlorine pesticides.
[PMID 23000097] Polymorphisms of catechol estrogens metabolism pathway genes and breast cancer risk in Mexican women.
[PMID 23021345] Gene-diet interactions on plasma lipid levels in the Inuit population.
[PMID 23107763] Host genetic risk factors for community-acquired pneumonia.
[PMID 23130019] Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations.
[PMID 23175176] Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.
[PMID 23178447] Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population.
[PMID 23661361] The potential effect of gender in CYP1A1 and GSTM1 genotype-specific associations with pediatric brain tumor.
[PMID 23832578] CYP1A1 exon7 polymorphism is associated with lung cancer risk among the female population and among smokers: a meta-analysis.
[PMID 23848208] CYP1A1 gene polymorphisms and polycystic ovary syndrome risk: a meta-analysis and meta-regression.
[PMID 23852617] Common polymorphisms in the CYP1A1 and CYP11A1 genes and polycystic ovary syndrome risk: a meta-analysis and meta-regression.
[PMID 24777039] A Multicenter Case-Control Study on Screening of Single Nucleotide Polymorphisms in Estrogen-Metabolizing Enzymes and Susceptibility to Uterine Leiomyoma in Han Chinese
[PMID 24068433] CYP1A1, GCLC, AGT, AGTR1 gene-gene interactions in community-acquired pneumonia pulmonary complications
[PMID 24939416] CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients
[PMID 24657182] Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer in a North Indian population
[PMID 25189712] The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China
[PMID 25928231] Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis
[PMID 26578427] CYP1A1 rs1048943 and rs4646903 polymorphisms associated with laryngeal cancer susceptibility among Asian populations: a meta-analysis
[PMID 27265845] The Association of CYP1A1 Gene With Cervical Cancer and Additional SNP-SNP Interaction in Chinese Women.
[PMID 27383824] The association of CYP1A1 genetic polymorphisms and additional gene-gene interaction with ischemic stroke in the eastern Han of China.
[PMID 28433806] Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh.
[PMID 28513235] Impact of interaction between CYP1A1 genetic polymorphisms and smoking on coronary artery disease in the Han of China.
[PMID 28620991] Potential Positive Association between Cytochrome P450 1A1 Gene Polymorphisms and Recurrent Pregnancy Loss: a Meta-Analysis.