rs1041740

plus

Geno	Mag	Summary
(C;C)	0	common/normal
(T;T)	1.8	Slight increase in cardiovascular risk?

Make rs1041740(C;T)

Reference

GRCh38 38.1/141

Chromosome

21

Position

31667849

Gene

SOD1

is a	snp
is	mentioned by
dbSNP	rs1041740
dbSNP (classic)	rs1041740
ClinGen	rs1041740
ebi	rs1041740
HLI	rs1041740
Exac	rs1041740
Gnomad	rs1041740
Varsome	rs1041740
LitVar	rs1041740
Map	rs1041740
PheGenI	rs1041740
Biobank	rs1041740
1000 genomes	rs1041740
hgdp	rs1041740
ensembl	rs1041740
geneview	rs1041740
scholar	rs1041740
google	rs1041740
pharmgkb	rs1041740
gwascentral	rs1041740
openSNP	rs1041740
23andMe	rs1041740
SNPshot	rs1041740
SNPdbe	rs1041740
MSV3d	rs1041740
GWAS Ctlg	rs1041740

GMAF

0.2626

Max Magnitude

1.8

A study of ~2800 Japanese adults concluded that rs1041740(T;T) was associated with cardiovascular mortality (adjusted HR, 2.07, CI: 1.10–3.91, p = 0.0244).[PMID 27755600 ]

?

(C;C) (C;T) (T;T)

28

[PMID 22357533] [Association between SNPs in SOD1 and noise-induced hearing loss in Chinese Han population]

[PMID 19306335 ] Interaction between a chromosome 10 RET enhancer and chromosome 21 in the Down syndrome-Hirschsprung disease association.

[PMID 21963083] Allelic variations in superoxide dismutase-1 (SOD1) gene are associated with increased risk of diabetic nephropathy in type 1 diabetic subjects.

[PMID 22608880] Allelic variations in superoxide dismutase-1 (SOD1) gene and renal and cardiovascular morbidity and mortality in type 2 diabetic subjects