Gs141
From SNPedia
| Gs141 | |
|---|---|
| Magnitude | 3.5 |
| Repute | Bad |
| Summary | 2x risk of Alzheimer's disease |
| Criteria | Gs141/criteria |
You carry one APOE-ε3 allele and one APOE-ε4 allele. This results in 2x-3x increased relative risk of Alzheimer's disease compared to those carrying two APOE-ε3 alleles. For non-Caucasians the risk is increased, but SNPedia has not yet seen any reliable estimates.
This is based on
Community[edit]
Learning while you are healthy that your odds of developing Alzheimer's may be higher than average by the time you are 80 years old can be a shock. Some of the people who have learned about their higher risk have formed ApoE4.info, a non-profit for ApoE4 carriers to discuss research and provide support. This includes a research wiki and a discussion forum.
Genoset gs216 identifies carriers of two ApoE-ε4 alleles.
