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From SNPedia
ExPublic Genomes
Summary Male on deCODEme and 23andMe v2

Jerry Emanuelson is the creator of http://www.futurescience.com/ and has wondered if his rs17703883(C;C) may have contributed to his familial osteoporosis. This SNP indicates a variant in the gene that codes for the aromatase enzyme. Results of his subsequent blood tests, with an unusually high ratio of free testosterone to estradiol, have tended to confirm a problem with the aromatase enzyme.

After using supplemental topical estradiol for 10 months, the preliminary results of a DEXA bone density scan on May 6, 2009 indicated an increase in lumbar spinal density of 20.1 percent over the previous year, which is a very substantial increase in bone density over a one year period. This is further confirmation of the possible linkage of rs17703883(C;C) to his familial osteoporosis.

A DEXA bone density scan in December, 2010 indicated a further increase in lumbar spinal bone density of 16.7 percent over the previous year. There has been a net gain of 32.7 percent in lumbar spinal bone density since mid-2008, when I first found clues to the causes of the spinal osteoporosis in my first SNP scan. I no longer have osteoporosis in either the spine or the hip.

A DEXA bone density scan in June, 2012 indicated a 42.5 percent increase in lumbar spinal bone density compared to the minimum in mid-2008. I will probably be getting another DEXA scan later in 2013.

The graphical summary of my DEXA bone scans summarizing the scans for both the spine and the hip from 2007 to 2012 are on the futurescience.com web site along with my comprehensive blood tests from 2007 to 2010. Links to that personal medical data, along with my own comments and relevant medical journal references are on the futurescience.com site at:

 Jerry's comments on his DNA SNP scans