The (A;A) type may be a "bad" SNP.
The studies about citalopram being more effective for (A;A) may indicate that one source of depression is a change in expression or activity of these receptors, which are acted upon by citalopram. This would imply that the (A;A) type is more susceptible to depression that happens to be more treatable with citalopram, while (G;G) types have depression with different cause(s), and are thus less affected by citalopram.
- I'm open to removing the current 'good' on (A;A) repute, if you can provide a citation for one such study. --- cariaso 04:39, 4 March 2016 (UTC)