TTR

is a	gene
is	mentioned by
Full name	transthyretin
EntrezGene	7276
PheGenI	7276
VariationViewer	7276
ClinVar	TTR
GeneCards	TTR
dbSNP	7276
Diseases	TTR
SADR	7276
HugeNav	7276
wikipedia	TTR
google	TTR
gopubmed	TTR
EVS	TTR
HEFalMp	TTR
MyGene2	TTR
23andMe	TTR
UniProt	P02766
Ensembl	ENSG00000118271
OMIM	176300
# SNPs	64

	Max Magnitude	Chromosome position
i3002758		29,172,937
i3002759		29,178,618
i5004213		29,175,120
i6019130
rs104894664	0	31,592,959
rs104894665	0	31,593,017
rs11541790	0	31,592,956
rs11541796	0	31,593,011
rs121918068	0	31,592,983
rs121918069	0	31,595,152
rs121918070	4	31,595,157
rs121918071	0	31,595,209
rs121918072	0	31,595,230
rs121918073	0	31,598,622
rs121918074	0	31,595,247
rs121918075	0	31,598,632
rs121918076	0	31,595,129
rs121918077	0	31,592,992
rs121918078	0	31,593,019
rs121918079	0	31,595,143
rs121918080	0	31,595,128
rs121918081	0	31,595,124
rs121918082	0	31,595,244
rs121918083	0	31,592,914
rs121918084	0	31,595,191
rs121918085	0	31,595,181
rs121918086	0	31,595,160
rs121918087	0	31,598,581
rs121918088	0	31,598,631
rs121918089	0	31,598,610
rs121918090	0	31,593,026
rs121918091	0	31,595,169
rs121918092	0	31,598,617
rs121918093	0	31,592,944
rs121918094	0	31,592,921
rs121918095	0	31,598,602
rs121918096	0	31,598,655
rs121918097	0	31,595,137
rs121918098	0	31,592,939
rs121918099	0	31,595,170
rs121918100	0	31,595,184
rs138065384	0	31,593,016
rs1800458	0	31,592,902
rs267607160	0	31,595,189
rs267607161	4	31,598,580
rs28933979	4	31,592,974
rs28933980	0	31,598,655
rs28933981	0	31,598,647
rs28933982	0	31,598,617
rs28933983	0	31,595,170
... further results

Located on chromosome 18, the TTR gene encodes the transthyretin protein, a transport protein in the serum and cerebrospinal fluid that carries the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. Mutations in the TTR gene may lead to several forms of amyloidosis.Wikipedia

Three such mutations account for roughly 50 - 80% of all TTR-related hereditary amyloidosis cases; these are:

rs76992529: aka VI122I, most common in African Americans and people of West African descent
rs28933979: aka V30M, most common in people of Portuguese, Northern Swedish, and Japanese descent
rs121918070: aka T60A, most common in people of Irish and British descent.