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SIRT1

From SNPedia
is agene
is mentioned by
Full namesirtuin 1
EntrezGene23411
PheGenI23411
VariationViewer23411
ClinVarSIRT1
GeneCardsSIRT1
dbSNP23411
DiseasesSIRT1
SADR23411
HugeNav23411
wikipediaSIRT1
googleSIRT1
gopubmedSIRT1
EVSSIRT1
HEFalMpSIRT1
MyGene2SIRT1
23andMeSIRT1
UniProtQ96EB6
EnsemblENSG00000096717
OMIM604479
# SNPs23
 Max MagnitudeChromosome positionSummary
rs1099787067,908,257
rs1099787567,920,067
rs1159917667,894,017
rs1241311267,892,108
rs1277836667,883,321
rs14412400267,887,495
rs146756867,915,401
rs223631867,888,811
rs223631967,889,462
rs2273773067,906,841
rs239444367,884,583
rs3395786167,887,218
rs3470170567,908,026
rs3568914567,900,009
rs3570687067,883,859
rs3610778167,891,561
rs3740051067,884,201
rs37583912.467,883,584
rs4746720067,917,073
rs706910267,903,362
rs77302570767,908,022
rs789600567,891,367
rs93265867,884,459

news SIRT1 seems to prevent a decline in levels of BDNF. People with Huntington disease tend to have low levels of BDNF.

http://www.cell.com/cell-metabolism/abstract/S1550-4131(13)00049-1 Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes