|| Reduced risk of testicular cancer
|| reduced risk of testicular cancer in men
|| non-protective against testicular cancer
|?|| (A;A) (A;G) (G;G) ||28|
23andMe blog each rs4624820(G) increases the odds of testicular cancer by 2.5x.
As reported by the CPMC, relative to men who are rs995030(G;G), men who are rs995030(A;G) have a 0.38 relative risk, and those who are (A;A) have a 0.15 relative risk.
] Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour
[PMID 22194441] Variants in KITLG predispose to testicular germ cell cancer independently from spermatogenic function.
[PMID 16905672] Association of genetic markers within the KIT and KITLG genes with human male infertility.
[PMID 19483682] Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|| Insufficiently evaluated pathogenic
[PMID 24083421] SNPs in KIT and KITLG genes may be associated with oligospermia in Chinese population