| CG genotype increases Alzheimer's risk relative to GG in epsilon 4s |
| Geno
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Mag
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Summary
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| (C;C)
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2.1
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CC genotype increases risk of Alzheimer's in epsilon 4s.
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| (C;G)
|
2.1
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CG genotype increases Alzheimer's risk relative to GG in epsilon 4s
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| (G;G)
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2.1
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Reduces risk of Alzheimer's in those with epsilon 4
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The risk of AD among those carrying an epsilon 4 and heterozygote gentotype at rs9472817 was intermediate between the other two homozygous genotypes. In the study cited for this SNP no specific p value is given for this heterozygote zygote result, though the CG genotype when considered in conjunction with epsilon 4 carriage yielded a p-value of p=1.02 * 10-13.
