CC genotype increases risk of Alzheimer's in epsilon 4s. |
Geno
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Mag
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Summary
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(C;C)
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2.1
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CC genotype increases risk of Alzheimer's in epsilon 4s.
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(C;G)
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2.1
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CG genotype increases Alzheimer's risk relative to GG in epsilon 4s
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(G;G)
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2.1
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Reduces risk of Alzheimer's in those with epsilon 4
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The article on the SNP page noted that those with CC and APOE epsilon 4 had increased risk of Alzheimer's as compared with those only with epsilon 4. This result will need to be confirmed in a larger study. Also it is not clear what the implications are for those with homozygous epsilon 4 genotype.