|| <0.62x risk for restless legs
|| 0.62x risk for restless legs
|?|| (C;C) (C;T) (T;T) ||28|
, a SNP located in the BTBD9
gene region, has been linked to a lower frequency of restless legs syndrome
, a common sleep disorder, with an overall odds ratio of 0.62 (CI: 0.52-0.75) for the (C) minor allele. [PMID 17637780
|Desc||RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 6|
] Exploring the genetic link between RLS and ADHD
[PMID 19279021] Replication of restless legs syndrome loci in three European populations.
|| Insufficiently evaluated pathogenic
[PMID 22914617] Analysis of the BTBD9 and HTR2C variants in Chinese Han patients with Tourette syndrome.
[PMID 22486183] A genetic risk factor for low serum ferritin levels in Danish blood donors.
Homozygosity for the T-allele of BTBD9 rs9296249 was associated with lower serum ferritin. The odds ratio for low serum ferritin was 1.35 (95% confidence interval, 1.02-1.77; p=0.03) when comparing donors with the TT genotype with donors with the CT genotype.
[PMID 28329290] Association of BTBD9 and MAP2K5/SKOR1 With Restless Legs Syndrome in Chinese Population.