||3x increased risk for developing a peanut allergy, 0.54x risk of IgA Nephropathy in Chinese
||1.7x increased risk for developing a peanut allergy, 0.54x risk of IgA Nephropathy in Chinese
rs9275596 is a SNP located between the HLA-DQB1 and HLA-DQA2 genes on chromosome 6.
A study of several thousand children and their parents, most with food allergies, concluded that two SNPs, rs7192 and rs9275596, are associated with increased susceptibility to developing a peanut allergy in populations of European ancestry. The odds ratio reported for rs9275596(C) were 1.7 (p=10e-10).[PMID 25710614]
||Genome-wide association study identifies susceptibility loci for IgA nephropathy
[PMID 18204098] Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
[PMID 19010793] Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.
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[PMID 28929317] Risk alleles for IgA nephropathy-associated SNPs conferred completely opposite effects to idiopathic membranous nephropathy in Chinese Han.