rs890

minus

Geno	Mag	Summary
(T;T)	0	common in clinvar

Make rs890(G;G)

Make rs890(G;T)

Reference

GRCh38 38.1/141

Chromosome

12

Position

13562374

Gene

GRIN2B

is a	snp
is	mentioned by
dbSNP	rs890
dbSNP (classic)	rs890
ClinGen	rs890
ebi	rs890
HLI	rs890
Exac	rs890
Gnomad	rs890
Varsome	rs890
LitVar	rs890
Map	rs890
PheGenI	rs890
Biobank	rs890
1000 genomes	rs890
hgdp	rs890
ensembl	rs890
geneview	rs890
scholar	rs890
google	rs890
pharmgkb	rs890
gwascentral	rs890
openSNP	rs890
23andMe	rs890
SNPshot	rs890
SNPdbe	rs890
MSV3d	rs890
GWAS Ctlg	rs890

GMAF

0.3283

Max Magnitude

0

?

(G;G) (G;T) (T;T)

28

[PMID 22578441] Lack of an association between obsessive-compulsive disorder and polymorphisms in the 3' untranslated region of GRIN2B in a Chinese Han population

[PMID 18303265] Association analysis of GRIN2B, encoding N-methyl-D-aspartate receptor 2B subunit, and Alzheimer's disease.

[PMID 19324536 ] Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder.

[PMID 20197096 ] Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.

[PMID 24114429] A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression

[PMID 23660601] Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive-compulsive symptoms.

ClinVar
Risk	rs890(G;G)
Alt	rs890(G;G)
Reference	Rs890(T;T)
Significance	Probable-non-pathogenic
Disease	Intellectual Disability
Variation	info
Gene	GRIN2B
CLNDBN	Intellectual Disability, Dominant
Reversed	1
HGVS	NC_000012.11:g.13715308A>C
CLNSRC
CLNACC	RCV000339902.1,