rs80359770

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359770(A;A)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32332434

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359770
dbSNP (classic)	rs80359770
ClinGen	rs80359770
ebi	rs80359770
HLI	rs80359770
Exac	rs80359770
Gnomad	rs80359770
Varsome	rs80359770
LitVar	rs80359770
Map	rs80359770
PheGenI	rs80359770
Biobank	rs80359770
1000 genomes	rs80359770
hgdp	rs80359770
ensembl	rs80359770
geneview	rs80359770
scholar	rs80359770
google	rs80359770
pharmgkb	rs80359770
gwascentral	rs80359770
openSNP	rs80359770
23andMe	rs80359770
SNPshot	rs80359770
SNPdbe	rs80359770
MSV3d	rs80359770
GWAS Ctlg	rs80359770

Max Magnitude

6

rs80359770, also known as 1184insA, c.956_957insA and p.Asn319?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359770(A;A)
Alt	rs80359770(A;A)
Reference	Rs80359770(-;-)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32906571dupA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045857.2, RCV000077045.6, RCV000166558.2, RCV000213917.2, RCV000467638.1,