rs80359650

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(-;AA)	6	BRCA2 variant considered pathogenic for breast cancer
(AA;AA)	0	common in clinvar

Make rs80359650(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32355267

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359650
dbSNP (classic)	rs80359650
ClinGen	rs80359650
ebi	rs80359650
HLI	rs80359650
Exac	rs80359650
Gnomad	rs80359650
Varsome	rs80359650
LitVar	rs80359650
Map	rs80359650
PheGenI	rs80359650
Biobank	rs80359650
1000 genomes	rs80359650
hgdp	rs80359650
ensembl	rs80359650
geneview	rs80359650
scholar	rs80359650
google	rs80359650
pharmgkb	rs80359650
gwascentral	rs80359650
openSNP	rs80359650
23andMe	rs80359650
SNPshot	rs80359650
SNPdbe	rs80359650
MSV3d	rs80359650
GWAS Ctlg	rs80359650

Max Magnitude

6

rs80359650, also known as 7642delAA, c.7414_7415delAA and p.Lys2472Valfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359650(-;-)
Alt	rs80359650(-;-)
Reference	Rs80359650(AA;AA)
Significance	Pathogenic
Disease	Breast-ovarian cancer Familial cancer of breast Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Familial cancer of breast Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32929404_32929405delAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031676.6, RCV000045203.2, RCV000131030.3,