rs80359643

plus

Geno	Mag	Summary
(-;C)	6	BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80359643(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32355079

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359643
dbSNP (classic)	rs80359643
ClinGen	rs80359643
ebi	rs80359643
HLI	rs80359643
Exac	rs80359643
Gnomad	rs80359643
Varsome	rs80359643
LitVar	rs80359643
Map	rs80359643
PheGenI	rs80359643
Biobank	rs80359643
1000 genomes	rs80359643
hgdp	rs80359643
ensembl	rs80359643
geneview	rs80359643
scholar	rs80359643
google	rs80359643
pharmgkb	rs80359643
gwascentral	rs80359643
openSNP	rs80359643
23andMe	rs80359643
SNPshot	rs80359643
SNPdbe	rs80359643
MSV3d	rs80359643
GWAS Ctlg	rs80359643

Max Magnitude

6

rs80359643, also known as 7454delC, c.7226_7226delC and p.Pro2409Leufs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359643(-;-)
Alt	rs80359643(-;-)
Reference	Rs80359643(C;C)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32929216delC
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045170.2, RCV000113733.3,