rs80359609

plus

Geno	Mag	Summary
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer
(TT;TT)	0	common in clinvar

Make rs80359609(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32329473

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359609
dbSNP (classic)	rs80359609
ClinGen	rs80359609
ebi	rs80359609
HLI	rs80359609
Exac	rs80359609
Gnomad	rs80359609
Varsome	rs80359609
LitVar	rs80359609
Map	rs80359609
PheGenI	rs80359609
Biobank	rs80359609
1000 genomes	rs80359609
hgdp	rs80359609
ensembl	rs80359609
geneview	rs80359609
scholar	rs80359609
google	rs80359609
pharmgkb	rs80359609
gwascentral	rs80359609
openSNP	rs80359609
23andMe	rs80359609
SNPshot	rs80359609
SNPdbe	rs80359609
MSV3d	rs80359609
GWAS Ctlg	rs80359609

Max Magnitude

6

rs80359609, also known as 890delTT, c.662_663delTT and p.Phe221Serfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359609(-;-)
Alt	rs80359609(-;-)
Reference	Rs80359609(TT;TT)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32903610_32903611delTT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044997.2, RCV000113987.3, RCV000214324.1,