rs80359593

plus

Geno	Mag	Summary
(-;TTAAA)	6	Likely miscall in 23andMe v4 data; otherwise, BRCA2 variant considered pathogenic for breast cancer
(ATTAA;ATTAA)	0	common in clinvar
(TTAAA;TTAAA)	0	common in clinvar

Make rs80359593(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340801

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359593
dbSNP (classic)	rs80359593
ClinGen	rs80359593
ebi	rs80359593
HLI	rs80359593
Exac	rs80359593
Gnomad	rs80359593
Varsome	rs80359593
LitVar	rs80359593
Map	rs80359593
PheGenI	rs80359593
Biobank	rs80359593
1000 genomes	rs80359593
hgdp	rs80359593
ensembl	rs80359593
geneview	rs80359593
scholar	rs80359593
google	rs80359593
pharmgkb	rs80359593
gwascentral	rs80359593
openSNP	rs80359593
23andMe	rs80359593
SNPshot	rs80359593
SNPdbe	rs80359593
MSV3d	rs80359593
GWAS Ctlg	rs80359593

Max Magnitude

6

rs80359593, also known as 6674del5, c.6446_6450delTTAAA and p.Ile2149_Lys2150?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

23andMe name: i5010375

ClinVar
Risk	rs80359593(-;-)
Alt	rs80359593(-;-)
Reference	Rs80359593(ATTAA;ATTAA)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32914938_32914942delTTAAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044955.3, RCV000077376.5, RCV000162931.2,