rs80359526

plus

Geno	Mag	Summary
(-;TTAA)	6	BRCA2 variant considered pathogenic for breast cancer
(TAAT;TAAT)	0	common in clinvar
(TTAA;TTAA)	0	common in clinvar

Make rs80359526(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339976

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359526
dbSNP (classic)	rs80359526
ClinGen	rs80359526
ebi	rs80359526
HLI	rs80359526
Exac	rs80359526
Gnomad	rs80359526
Varsome	rs80359526
LitVar	rs80359526
Map	rs80359526
PheGenI	rs80359526
Biobank	rs80359526
1000 genomes	rs80359526
hgdp	rs80359526
ensembl	rs80359526
geneview	rs80359526
scholar	rs80359526
google	rs80359526
pharmgkb	rs80359526
gwascentral	rs80359526
openSNP	rs80359526
23andMe	rs80359526
SNPshot	rs80359526
SNPdbe	rs80359526
MSV3d	rs80359526
GWAS Ctlg	rs80359526

Max Magnitude

6

rs80359526, also known as 5849del4, c.5621_5624delTTAA and p.Ile1874_Lys1875?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359526(-;-)
Alt	rs80359526(-;-)
Reference	Rs80359526(TAAT;TAAT)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32914113_32914116delTTAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031561.7, RCV000131115.3, RCV000223208.2, RCV000416547.2,