rs80359496

plus

Geno	Mag	Summary
(-;TTTAAGT)	6	BRCA2 variant considered pathogenic for breast cancer
(TTTAAGT;TTTAAGT)	0	common in clinvar

Make rs80359496(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339572

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359496
dbSNP (classic)	rs80359496
ClinGen	rs80359496
ebi	rs80359496
HLI	rs80359496
Exac	rs80359496
Gnomad	rs80359496
Varsome	rs80359496
LitVar	rs80359496
Map	rs80359496
PheGenI	rs80359496
Biobank	rs80359496
1000 genomes	rs80359496
hgdp	rs80359496
ensembl	rs80359496
geneview	rs80359496
scholar	rs80359496
google	rs80359496
pharmgkb	rs80359496
gwascentral	rs80359496
openSNP	rs80359496
23andMe	rs80359496
SNPshot	rs80359496
SNPdbe	rs80359496
MSV3d	rs80359496
GWAS Ctlg	rs80359496

Max Magnitude

6

rs80359496, also known as 5445del7, c.5217_5223delTTTAAGT and p.Tyr1739_Ser1741?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359496(-;-)
Alt	rs80359496(-;-)
Reference	Rs80359496(TTTAAGT;TTTAAGT)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32913709_32913715delTTTAAGT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044613.3, RCV000077350.5, RCV000131077.4, RCV000219434.2,