rs80359395

plus

Geno	Mag	Summary
(-;TG)	6	BRCA2 variant considered pathogenic for breast cancer
(TG;TG)	0	common in clinvar

Make rs80359395(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338035

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359395
dbSNP (classic)	rs80359395
ClinGen	rs80359395
ebi	rs80359395
HLI	rs80359395
Exac	rs80359395
Gnomad	rs80359395
Varsome	rs80359395
LitVar	rs80359395
Map	rs80359395
PheGenI	rs80359395
Biobank	rs80359395
1000 genomes	rs80359395
hgdp	rs80359395
ensembl	rs80359395
geneview	rs80359395
scholar	rs80359395
google	rs80359395
pharmgkb	rs80359395
gwascentral	rs80359395
openSNP	rs80359395
23andMe	rs80359395
SNPshot	rs80359395
SNPdbe	rs80359395
MSV3d	rs80359395
GWAS Ctlg	rs80359395

Max Magnitude

6

rs80359395, also known as 3908delTG, c.3680_3681delTG and p.Leu1227Glnfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359395(-;-)
Alt	rs80359395(-;-)
Reference	Rs80359395(TG;TG)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32912172_32912173delTG
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044241.4, RCV000077311.6, RCV000131092.3, RCV000214590.1,