rs80359011

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;G)	6	BRCA2 variant considered pathogenic for breast cancer
(G;G)	0	common in clinvar

Make rs80359011(A;A)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32362574

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359011
dbSNP (classic)	rs80359011
ClinGen	rs80359011
ebi	rs80359011
HLI	rs80359011
Exac	rs80359011
Gnomad	rs80359011
Varsome	rs80359011
LitVar	rs80359011
Map	rs80359011
PheGenI	rs80359011
Biobank	rs80359011
1000 genomes	rs80359011
hgdp	rs80359011
ensembl	rs80359011
geneview	rs80359011
scholar	rs80359011
google	rs80359011
pharmgkb	rs80359011
gwascentral	rs80359011
openSNP	rs80359011
23andMe	rs80359011
SNPshot	rs80359011
SNPdbe	rs80359011
MSV3d	rs80359011
GWAS Ctlg	rs80359011

Max Magnitude

6

rs80359011, also known as W2619X, c.7857G>A and p.Trp2619Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359011(A;A)
Alt	rs80359011(A;A)
Reference	Rs80359011(G;G)
Significance	Pathogenic
Disease	Breast-ovarian cancer Familial cancer of breast Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Familial cancer of breast Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32936711G>A
CLNSRC	ClinVar
CLNACC	RCV000031704.6, RCV000045331.2, RCV000162936.1,