rs80358658

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;T)	6	BRCA2 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80358658(A;A)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338450

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80358658
dbSNP (classic)	rs80358658
ClinGen	rs80358658
ebi	rs80358658
HLI	rs80358658
Exac	rs80358658
Gnomad	rs80358658
Varsome	rs80358658
LitVar	rs80358658
Map	rs80358658
PheGenI	rs80358658
Biobank	rs80358658
1000 genomes	rs80358658
hgdp	rs80358658
ensembl	rs80358658
geneview	rs80358658
scholar	rs80358658
google	rs80358658
pharmgkb	rs80358658
gwascentral	rs80358658
openSNP	rs80358658
23andMe	rs80358658
SNPshot	rs80358658
SNPdbe	rs80358658
MSV3d	rs80358658
GWAS Ctlg	rs80358658

Max Magnitude

6

rs80358658, also known as C1365X, c.4095T>A and p.Cys1365Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80358658(A;A)
Alt	rs80358658(A;A)
Reference	Rs80358658(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32912587T>A
CLNSRC	ClinVar
CLNACC	RCV000044347.2, RCV000113273.2, RCV000447449.1,