rs80357770

minus

Geno	Mag	Summary
(-;A)	6	BRCA1 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80357770(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43094141

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357770
dbSNP (classic)	rs80357770
ClinGen	rs80357770
ebi	rs80357770
HLI	rs80357770
Exac	rs80357770
Gnomad	rs80357770
Varsome	rs80357770
LitVar	rs80357770
Map	rs80357770
PheGenI	rs80357770
Biobank	rs80357770
1000 genomes	rs80357770
hgdp	rs80357770
ensembl	rs80357770
geneview	rs80357770
scholar	rs80357770
google	rs80357770
pharmgkb	rs80357770
gwascentral	rs80357770
openSNP	rs80357770
23andMe	rs80357770
SNPshot	rs80357770
SNPdbe	rs80357770
MSV3d	rs80357770
GWAS Ctlg	rs80357770

Merged from

Rs273897658

Max Magnitude

6

rs80357770, also known as 1509delA, c.1390_1390delA and p.Thr464Profs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357770(-;-)
Alt	rs80357770(-;-)
Reference	Rs80357770(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41246158delT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047457.2, RCV000111604.5,