rs80357621

minus

Geno	Mag	Summary
(-;T)	6	BRCA1 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80357621(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43092000

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357621
dbSNP (classic)	rs80357621
ClinGen	rs80357621
ebi	rs80357621
HLI	rs80357621
Exac	rs80357621
Gnomad	rs80357621
Varsome	rs80357621
LitVar	rs80357621
Map	rs80357621
PheGenI	rs80357621
Biobank	rs80357621
1000 genomes	rs80357621
hgdp	rs80357621
ensembl	rs80357621
geneview	rs80357621
scholar	rs80357621
google	rs80357621
pharmgkb	rs80357621
gwascentral	rs80357621
openSNP	rs80357621
23andMe	rs80357621
SNPshot	rs80357621
SNPdbe	rs80357621
MSV3d	rs80357621
GWAS Ctlg	rs80357621

Max Magnitude

6

rs80357621, also known as 3650delT, c.3531_3531delT and p.Phe1177Leufs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357621(-;-)
Alt	rs80357621(-;-)
Reference	Rs80357621(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41244017delA
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000048224.3, RCV000112111.3,