|(A;A)||Individuals showed a significantly lower risk of suicide behavior than those with the A/G or G/G genotype|
|(A;G)||risk of suicide behavior|
|(G;G)||risk of suicide behavior|
[PMID 19763617] Involvement of tryptophan hydroxylase 2 (TPH2) gene polymorphisms in susceptibility to coronary artery lesions in Korean children with Kawasaki disease
[PMID 20738857] Effect of Tryptophan Hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression
[PMID 21620479] Tryptophan hydroxylase 2 gene is associated with major depressive disorder in a female Chinese population
[PMID 21969281] Influence of birth weight on internalizing traits modulated by serotonergic genes
[PMID 17649681] [A case-control study on the risk factors for attempted suicide in patients with major depression].
[PMID 18439448] Stress, genes and the biology of suicidal behavior.
[PMID 18698231] Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.
[PMID 19693267] Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
[PMID 20126463] Alternative splicing and extensive RNA editing of human TPH2 transcripts.
[PMID 20403506] Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.
[PMID 20938755] Association study of tryptophan hydroxylase-2 gene in schizophrenia and its clinical features in Chinese Han population.
[PMID 21172166] Pharmacogenetics of antidepressant response.
[PMID 21937687] Influence and interaction of genetic polymorphisms in the serotonin system and life stress on antidepressant drug response.
|qualified_impact||Insufficiently evaluated pharmacogenetic|
[PMID 22655589] Investigation of tryptophan hydroxylase 2 (TPH2) in schizophrenia and in the response to antipsychotics.
[PMID 23628433] Genetic association and gene-gene interaction analyses suggest likely involvement of ITGB3 and TPH2 with autism spectrum disorder (ASD) in the Indian population.
[PMID 25214390] Interaction among childhood trauma and functional polymorphisms in the serotonin pathway moderate the risk of depressive disorders
[PMID 26028568] Association analysis of TPH-1 and TPH-2 genes with suicidal behavior in patients with attempted suicide in Mexican population
[PMID 26057341] Tryptophan hydroxylase 2 gene is associated with cognition in late-onset depression in a Chinese Han population
[PMID 26232682] Genetic variability in tryptophan hydroxylase 2 gene in alcohol dependence and alcohol-related psychopathological symptoms