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rs7000448

From SNPedia

Orientationplus
Stabilizedplus
Make rs7000448(C;C)
Make rs7000448(C;T)
Make rs7000448(T;T)
ReferenceGRCh38 38.1/142
Chromosome8
Position127428925
GeneCASC8
is asnp
is mentioned by
dbSNPrs7000448
dbSNP (classic)rs7000448
ClinGenrs7000448
ebirs7000448
HLIrs7000448
Exacrs7000448
Gnomadrs7000448
Varsomers7000448
LitVarrs7000448
Maprs7000448
PheGenIrs7000448
Biobankrs7000448
1000 genomesrs7000448
hgdprs7000448
ensemblrs7000448
geneviewrs7000448
scholarrs7000448
googlers7000448
pharmgkbrs7000448
gwascentralrs7000448
openSNPrs7000448
23andMers7000448
SNPshotrs7000448
SNPdbers7000448
MSV3drs7000448
GWAS Ctlgrs7000448
GMAF0.416
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs7000448 increases susceptibility to Prostate cancer 1.19 times for carriers of the T allele [PMID 17401364OA-icon.png]


[PMID 20717903OA-icon.png] Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: The flint men's health study

[PMID 21051319OA-icon.png] Risk of Urinary Bladder Cancer is Associated with 8q24 Variant rs9642880[T]: Results from the Los Angeles-Shanghai Case-Control Study


[PMID 22234922OA-icon.png] 8q24 risk alleles in West African and Caribbean men

[PMID 17618282OA-icon.png] A common genetic risk factor for colorectal and prostate cancer.

[PMID 18231127OA-icon.png] 8q24 and prostate cancer: association with advanced disease and meta-analysis.

[PMID 18349290] Association of genetic variants at 8q24 with breast cancer risk.

[PMID 18360876OA-icon.png] Chromosome 8q24 markers: risk of early-onset and familial prostate cancer.

[PMID 18483343] Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.

[PMID 18577746OA-icon.png] Multiple loci with different cancer specificities within the 8q24 gene desert.

[PMID 19155440OA-icon.png] Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.

[PMID 19366828OA-icon.png] Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.

[PMID 19520795OA-icon.png] Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans.

[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.

[PMID 19549893OA-icon.png] Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

[PMID 19602258OA-icon.png] Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men.

[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.

[PMID 22382457OA-icon.png] Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.