|| 1.5x higher risk for hypertension
|| 1.2x higher risk for hypertension
|?|| (G;G) (G;T) (T;T) ||28|
has been reported in a large study to be associated with high blood pressure
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.20 (CI 0.94-1.52), and for homozygotes, 1.49 (CI 1.18-1.89). [PMID 17554300]
In a study of 7,551 Koreans, this SNP was associated with systolic and diastolic blood pressures in a quantitative trait association test but no associations were found using a case-control association test.[PMID 19424278]
[PMID 18523456] Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program.