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rs6968865

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0
(A;T) 1.2 Associated with (slightly) increased coffee consumption
(T;T) 1.2 Associated with (slightly) increased coffee consumption
ReferenceGRCh38 38.1/141
Chromosome7
Position17247645
is asnp
is mentioned by
dbSNPrs6968865
ClinGenrs6968865
ebirs6968865
HLIrs6968865
Exacrs6968865
Varsomers6968865
Maprs6968865
PheGenIrs6968865
hapmaprs6968865
1000 genomesrs6968865
hgdprs6968865
ensemblrs6968865
gopubmedrs6968865
geneviewrs6968865
scholarrs6968865
googlers6968865
pharmgkbrs6968865
gwascentralrs6968865
openSNPrs6968865
23andMers6968865
23andMe allrs6968865
SNP Nexus

SNPshotrs6968865
SNPdbers6968865
MSV3drs6968865
GWAS Ctlgrs6968865
GMAF0.4793
Max Magnitude1.2
rs6968865 is a SNP located near the aryl hydrocarbon receptor AHR gene on ch 7p21.

A meta-analysis of four GWAS studies of coffee consumption among a total of ~8,000 coffee drinkers of European ancestry found that the rs6968865(T) was strongly associated with increased consumption (p = 2.3 x 10e-11). The estimated effect was an increase of 0.2 cups a day per allele for both this SNP and one other (rs2472297).[PMID 21357676OA-icon.png]

? (A;A) (A;T) (T;T) 28
[PMID 22854411] Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption