||1.5x risk of rheumatoid arthritis
||1.2x risk of rheumatoid arthritis
rs6684865 has been reported in a large study to be associated with rheumatoid arthritis.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.27 (CI 1.02-1.56), and for homozygotes, 1.54 (CI 1.25-1.90). [PMID 17554300]
[PMID 20187130] Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis
[PMID 20962851] Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition
[PMID 18794857] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
[PMID 20017963] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.
[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.