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rs6094710

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.3 1.3x risk of osteoarthritis
(A;G) 1.3 1.3x risk of osteoarthritis
(G;G) 1 No increased risk of osteoarthritis
ReferenceGRCh38 38.1/142
Chromosome20
Position47466905
is asnp
is mentioned by
dbSNPrs6094710
dbSNP (old)rs6094710
ClinGenrs6094710
ebirs6094710
HLIrs6094710
Exacrs6094710
Gnomadrs6094710
Varsomers6094710
Maprs6094710
PheGenIrs6094710
Biobankrs6094710
1000 genomesrs6094710
hgdprs6094710
ensemblrs6094710
gopubmedrs6094710
geneviewrs6094710
scholarrs6094710
googlers6094710
pharmgkbrs6094710
gwascentralrs6094710
openSNPrs6094710
23andMers6094710
23andMe allrs6094710
SNP Nexus

SNPshotrs6094710
SNPdbers6094710
MSV3drs6094710
GWAS Ctlgrs6094710
Max Magnitude1.3
? (A;A) (A;G) (G;G) 28
[PMID 23989986OA-icon.png] 2014 study of 11,277 cases of radiographic and symptomatic hip osteoarthritis (OA). "One locus, at 20q13, represented by rs6094710 (minor allele frequency (MAF) 4%) near the NCOA3 (nuclear receptor coactivator 3) gene, reached genome-wide significance level with p=7.9×10(-9) and OR=1.28 (95% CI 1.18 to 1.39) in the combined analysis of discovery (p=5.6×10(-8)) and follow-up studies (p=7.3×10(-4)). We showed that this gene is expressed in articular cartilage and its expression was significantly reduced in OA-affected cartilage." (Abstract)
GWAS snp
PMID [PMID 23989986OA-icon.png]
Trait Osteoarthritis (hip)
Title A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.
Risk Allele A
P-val 2E-10
Odds Ratio 1.28 [1.18-1.39]