|| most common genotype, lower testosterone
|?|| (C;C) (C;T) (T;T) ||28|
] "Genetic determinants of serum testosterone concentrations in men" - The rs5934505 polymorphism near FAM9B on the X chromosome was also associated with testosterone concentrations (p?=?5.6×10(-16)). The mean serum testosterone and calculated free testosterone but not SHBG concentrations were lower in men with T genotype than in those with C genotype for rs5934505.
|| [PMID 22936694]
|| Androgen levels
|| Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
| Risk Allele
| Odds Ratio
|| .09 [0.060-0.122] unit increase
[PMID 23258625] Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality.
[PMID 26602056] The rs5934505 single nucleotide polymorphism (SNP) is associated with low testosterone and late-onset hypogonadism, but the rs10822184 SNP is associated with overweight and obesity in a Chinese Han population: a case-control study