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rs56038477

From SNPedia

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Stabilizedplus
Geno Mag Summary
(C;C) 0 common/normal
(C;T) 2 Carrier of a decreased function DPYD gene allele
(T;T) 3.5 Likely toxicity if treated with certain fluoropyrimidine-based chemotherapeutics
is asnp
is mentioned by
dbSNPrs56038477
dbSNP (classic)rs56038477
ClinGenrs56038477
ebirs56038477
HLIrs56038477
Exacrs56038477
Gnomadrs56038477
Varsomers56038477
LitVarrs56038477
Maprs56038477
PheGenIrs56038477
Biobankrs56038477
1000 genomesrs56038477
hgdprs56038477
ensemblrs56038477
geneviewrs56038477
scholarrs56038477
googlers56038477
pharmgkbrs56038477
gwascentralrs56038477
openSNPrs56038477
23andMers56038477
23andMe allrs56038477
SNPshotrs56038477
SNPdbers56038477
MSV3drs56038477
GWAS Ctlgrs56038477
Max Magnitude3.5

aka c.1236G>A (p.Glu412= or 412E); decreased function DPYD gene allele

PharmGKB notes that cancer patients carrying a rs56038477(T) allele treated with fluoropyrimidine-based chemotherapy may have an increased risk for drug toxicities as compared to patients with the (C;C) genotype.