|?|| (G;G) (G;T) (T;T) ||28|
linked to obesity
|Desc||LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5; LRP5|
] Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.
[PMID 17002564] Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction.
[PMID 17903296] Genome-wide association with bone mass and geometry in the Framingham Heart Study.
[PMID 18455228] Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.
[PMID 25762437] Strong effect of SNP rs4988300 of the LRP5 gene on bone phenotype of Caucasian postmenopausal women