rs4987047

plus

Geno	Mag	Summary
(A;A)	0	common in complete genomics
(T;T)	2

Make rs4987047(A;T)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32379392

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs4987047
dbSNP (classic)	rs4987047
ClinGen	rs4987047
ebi	rs4987047
HLI	rs4987047
Exac	rs4987047
Gnomad	rs4987047
Varsome	rs4987047
LitVar	rs4987047
Map	rs4987047
PheGenI	rs4987047
Biobank	rs4987047
1000 genomes	rs4987047
hgdp	rs4987047
ensembl	rs4987047
geneview	rs4987047
scholar	rs4987047
google	rs4987047
pharmgkb	rs4987047
gwascentral	rs4987047
openSNP	rs4987047
23andMe	rs4987047
SNPshot	rs4987047
SNPdbe	rs4987047
MSV3d	rs4987047
GWAS Ctlg	rs4987047

GMAF

0.007805

Max Magnitude

2

?

(A;A) (A;T) (T;T)

28

This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (T).

ClinVar
Risk	Rs4987047(T;T)
Alt	Rs4987047(T;T)
Reference	Rs4987047(A;A)
Significance	Other
Disease	not provided Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer not specified Hereditary cancer-predisposing syndrome Fanconi anemia Neoplasm of breast Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	not provided Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 not specified Hereditary cancer-predisposing syndrome Fanconi anemia Neoplasm of breast Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32953529A>T
CLNSRC	Ambry Genetics ClinVar Counsyl GeneDx
CLNACC	RCV000034467.3, RCV000045638.9, RCV000083150.7, RCV000120365.6, RCV000131023.2, RCV000317148.1, RCV000413753.1, RCV000463955.1,