||carrier of one CYP3A4*3 allele
rs4986910, also known as 1334T>C, 23171T>C or M445T, is a SNP in the CYP3A4 gene.
The rs4986910(C) allele defines the CYP3A4*3 variant.
[PMID 19214745] Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists
[PMID 17615053] Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.
[PMID 19076156] Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.